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From yearlings to 20-year-old stallions,
and in every discipline from Dressage to Cutting Horses,
Cosequin® success stories continue to pour in. Regardless of
age, breed or discipline, the stress of training and
competition causes wear and tear to articular cartilage,
eventually compromising optimal joint function and
dramatically affecting the performance of the equine athlete.
Cosequin plays an important role in
maintaining optimal joint function. The superior quality
ingredients in our patented formula provide the raw materials
that are essential for the synthesis of synovial fluid and the
major components of articular cartilage matrix. The
synergistic effect of each ingredient performing its primary
function concurrently is what makes Cosequin unique and the
only true broad-spectrum cartilage matrix enhancer.
Unlike steroids and some NSAID's which can
damage the cartilage matrix, Cosequin is not a drug; it is a
true nutraceutical with unparalleled safety. Nothing comes
close to matching the confidence and reliability of the clean,
patented formulation that has helped make Cosequin an industry
leader.
Joints and Articular Cartilage
The performance and mobility of your
horse is dramatically affected by how well his joints
function. While physical conditioning can strengthen muscles,
bones, and tendons, the tremendous forces exerted on the
skeletal joints (fetlock, knee, stifle and hock) during
training and competition causes wear and tear to the joint
cartilage. Articular cartilage is critical to joint utility.
Immersed in synovial fluid, articular cartilage provides a
smooth, low friction surface between bone ends, and transmits
load forces to the underlying bones.
Why Cosequin?
One of the remarkable functions of articular
cartilage is its ability to replenish its major components in
response to the mechanical forces placed on it.
Cartilage replenishes itself by manufacturing huge amounts of
collagen and proteoglycans. Collagen, a tough, ropy protein
that connects the tissues, provides the tensile strength of
cartilage. The water-structuring properties of proteoglycans
provide the compressive resilience. The continuous
synthesizing process of cartilage replenishment generates
extremely large demands for the building blocks of collagen
and proteoglycans. If the raw materials (nutrients) for these
building blocks are not available in the amounts required, the
synthesizing process is impaired and the cartilage cannot
replenish itself.
Cosequin provides these raw materials.
Cosequin is a patented combination of dietary ingredients of
unparralleled purity and each has its own primary function in
connective tissues synthesis.
- Glucosamine HCL - In addition to being
the main substrate for the biosynthesis of
glycosaminoglycans and hyaluronic acid, the primary
function of glucosamine is to stimulate the secretion of
glycosaminoglycans in the articular cartilage.
- Chondroitin Sulfate - In addition to
being the major glycosaminoglycans found in cartilage, its
primary function is to inhibit degradative enzymes.
Degradative enzymes contribute to cartilage breakdown.
- Manganese - A necessary cofactor in the
body for the biosynthesis of glycosaminoglycans.
- Ascorbate - It is a necessary cofactor in
the body for collagen biosynthesis.
The synergistic effect of glucosamine and
chondroitin sulfate performing their primary functions
concurrently, using manganese and ascorbate as cofactors, is
what makes Cosequin unique and the only product of its kind.
This overall matrix enhancement will make Cosequin more
economical to use the longer an animal is on the product.
The ingredients in Cosequin are of
unparalleled purity. A multiple-step purification process
ensures maximum ingredient integrity.
What can I expect using Cosequin?
Since Cosequin provides nutrients that
affect the structure and function of the joint, changes may
occur gradually. You should notice changes in three to four
weeks in most candidates. Some horses may take five to six
weeks to exhibit noticeable changes.
Recommendation as a Dietary Supplement
The initial administration period is 4 to 6
weeks, however recent studies using Cosequin have shown an
early response, in most horses, by 2 weeks. The reponse
usually improves if the initial amount is continued for an
additional 4 weeks. If a horse shows little or no response
after 30 days, extend initial amount for two more weeks.
Initial Administration
Average Horse - 3 level scoops AM & PM
Horses over 1,200 lb. - 4 level scoops AM & PM
Overly large horses (warmbloods, draft breeds) may need 4 or 5
scoops AM & PM
Transition Period
Do not lower amount until horse has begun to
respond. After achieving a good response, reduce total daily
amount by one level scoop each week. Gradually reducing the
amount will help find an individual maintenance level. Watch
the animal's movement and attitude to ensure that it is
feeling comfortable through each weekly transition.
Suggested Maintenance Administration
Average Horse - 1 level scoop AM & PM
Horses over 1,200 lb. - 2 level scoops AM & PM
Amount can be increased at any time to maintain desired
comfort level. Two or three days prior to heavy workouts or
competition, boost daily dosage back up to initial loading
dose. Continue this level for two to three days after
competition, then return to regular maintenance level.
Directions
Cosequin can be top dressed on sweet feed.
Add a small amount of water or molasses to get the Cosequin to
stick to dry feed. You may also administrate orally. Mix
Cosequin with a small amount of water or molasses and dose
orally with a syringe.
Are there any side effects with Cosequin?
Cosequin is very safe to use. Acute oral
toxicity tests have been conducted indicating no oral
toxicity. The tests indicated an LD-50 greater than 5 gm/kg
which is the standard for nontoxic substances. In addition,
fungal and microbial tests are run on each batch of Cosequin
to ensure the product is free of pathogens. Cosequin is a true
nutraceutical with outstanding safety.
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